Monksland has a long manufacturing tradition and today is justifiably proud to be regarded as the epicentre of all commercial and industrial activity in the Midlands. Companies with a high and international reputation such as Elan Corporation, Bioclin & Pharmplaz are located in Monksland Industrial Estate.

Athlone town is the regional centre for a large number of state and semi-state organisations. These account for some 3000 odd jobs and contribute substantially to the business life of the town i.e. Defence Forces (including military personnel and civilians), Department of Education, Athlone Institute of Technology, FAS Midlands Region, CIE, IDA, Enterprise Ireland, Eircom, Health Services, Athlone Town Council, Schools and various Government Departments.

The Services Sector employs half the population of the Midlands region, Industry comes second, with agriculture still a significant employer, but declining in third place.